Treatment Overview
When you get immunotherapy in the form of allergy shots,
		  your
		  allergist or doctor injects small doses of substances
		  that you are allergic to (allergens) under your skin. This helps
		  your body "get used to" the allergen, which can result in fewer or less severe
		  symptoms of
		  allergic rhinitis.
Your allergist will
		  use an extract of grass, weed, or tree pollen;
		  dust mites; molds; or
		  animal dander for allergy shots. You must first have
		  skin testing to find out which allergen you are allergic to.
Your
		  allergist injects under your skin a solution of salt water (saline) that
		  contains a very small amount of the allergen(s). At first, you get the shot
		  once or twice a week. You gradually receive more of the allergen in the shots.
After about 4 to 6 months of weekly shots, you are usually
		  getting the best amount of allergen in the shot. This is called the maintenance
		  dose. When you reach the maintenance dose, you get the same dose in shots every
		  2 to 4 weeks for the next 4 to 6 months.
The period between shots
		  is gradually increased to about a month. And the dose usually stays the same
		  each month. After 1 year of maintenance, your allergist will check to see if
		  you have fewer or less severe symptoms. If your allergy symptoms have not
		  changed, you will no longer get the shots. If your symptoms have improved, you
		  may continue to get monthly shots for up to 3 to 5 years.footnote 1
Other ways to get this treatment are called
		  cluster or
		  rush immunotherapy, in which you reach the maintenance
		  dose more quickly. 
What To Expect After Treatment
You receive allergy shots in your
		  allergist's office. You will stay in the office for 30 minutes after you
		  get the shots, in case you have a severe reaction (anaphylaxis) to
		  the injected allergens.
Redness and warmth at the shot site are
		  common. But these go away after a short period of time.
Why It Is Done
Allergy shots can reduce your
		  reaction to allergens, which can result in fewer or less severe symptoms. They
		  may also prevent children who have allergic rhinitis from getting
		  asthma.footnote 1 Recommendations on when to get allergy shots vary, but in general you and your
		  doctor may consider them when:
- Allergy symptoms are severe enough that the
			 benefit from the shots outweighs the expense and the time spent getting the
			 shots.
- You are allergic to only a few substances, and they are hard
			 to avoid.
- Avoiding allergens and using medicine do not control
			 symptoms, or you have to take medicine all the time to control
			 symptoms.
- Side effects of medicines are a problem.
- You
			 want a treatment for the cause of your allergy, rather than treatment for just
			 the symptoms.
- You have another condition that is being affected by
			 allergic rhinitis, such as asthma.
- You want to lower the chance
			 that you will develop asthma.
How Well It Works
Allergy shots are effective in
		  treating allergic rhinitis and
		  allergic asthma. The shots
		  reduce symptoms in those allergic to pollens,
		  animal dander,
		  dust mites, mold, and cockroaches. Experts do not know how long allergy shots work
		  after you stop getting the shots. Some people may not have their allergies return. Others may have allergies return within a few years.footnote 1
Although you still need to avoid allergens, you may be able
		  to use less medicine or stop using medicines.
Risks
Allergy shots almost always
		  are safe if given correctly. Redness and warmth at the shot site are common.
		  Overall body reactions, such as
		  hives, asthma symptoms, and low
		  blood pressure, are not common. Because of the
		  possibility of a life-threatening reaction (anaphylaxis),
		  you get the shots where emergency care is available.
If you or
		  your child has another condition, such as
		  asthma, you may be more likely to have a severe
		  reaction to the shots. You should have your asthma well controlled before you
		  get allergy shots. 
What To Think About
Although expensive, allergy shots
		  may cost no more than the combined cost of medicine, doctor and emergency room
		  visits, and missed days of school or work over several years. But you may need
		  to take regular shots for 3 to 5 years. And it may take a year or more for
		  symptoms to improve. If the treatment schedule would be hard for you to
		  follow, you may want to think about other options. During your treatment, you
		  should see your doctor at least once every 6 to 12 months.
Allergy
		  shots treat an allergy to just one allergen or a very closely related group of
		  them, such as grass pollens. If you are allergic to more than one type of
		  allergen, you may need to receive shots for each type of allergen to relieve
		  all of your symptoms. The allergens can usually be combined into one or two
		  shots.
Children younger than 2 should not have allergy shots.
		  Children ages 3 to 4 may find it hard to get many shots over a long
		  period of time. Talk with your doctor about whether allergy shots are right for
		  your child.
Older adults may be taking medicines or have other
		  medical conditions that may increase the risk of a severe reaction to allergy
		  shots.
You must report any delayed reaction to an allergy shot.
		  Late reactions can happen any time within 24 hours after a shot. Reactions may
		  just affect the injection site (such as a large, red or raised area around the
		  site) or they may affect your overall body (such as trouble breathing).
Pregnant women who are already taking allergy shots may continue them.
		  But do not start taking them during pregnancy.
Allergy shots
		  should not be used when you:
- Have had a recent
			 heart attack,
			 unstable angina, or other heart problems or are taking
			 beta-blockers.
- Are unable to communicate
			 (can't tell your doctor about reactions to shots). Most doctors do not give
			 allergy shots to children younger than 5.
- Have an immune system
			 disease (such as
			 AIDS).
Sublingual immunotherapy may be another way to treat certain pollen allergies. Instead of getting shots, you dissolve a tablet under your tongue daily. Each tablet has a small amount of allergen in it. This treatment, like allergy shots, helps your body "get used to" the allergen, so your body reacts less to it over time. Oral and sublingual immunotherapy is being studied for other types of allergies also.
- Allergies: Should I Take Allergy Shots?
Complete the special treatment information form (PDF)(What is a PDF document?) to help you understand this treatment.
References
Citations
- Joint Task Force on Practice Parameters (2011). Allergen immunotherapy: A practice parameter third update. Journal of Allergy and Clinical Immunology, 127(1, Suppl): S1-S55.
Credits
ByHealthwise Staff
Primary Medical ReviewerE. Gregory Thompson, MD - Internal Medicine
Specialist Medical ReviewerMartin J. Gabica, MD - Family Medicine
Current as ofApril 3, 2017