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How an Imbalanced Gut Microbiome Worsens Chronic Kidney Disease

Researchers at UC Davis School of Medicine have uncovered how an imbalanced gut microbiome escalates the production of metabolic byproducts by certain gut bacteria. This imbalance drives a feedback loop that worsens chronic kidney disease (CKD) in mice. The scientists identified an investigational drug that might break the destructive cycle. The findings were published in Science.

March 19, 2026


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