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Young Adults Still Face Rising Gastric Cancer Disparities Amid Overall Decline

The global burden of early-onset gastric cancer (EOGC) has decreased over the past three decades, yet regional, gender, and socioeconomic disparities remain pronounced. This large-scale analysis, covering data from 1990 to 2021 and projecting trends to 2040, identified smoking and high-salt dietary intake as the leading modifiable risk factors. While public health interventions have effectively lowered incidence and mortality, the disease continues to disproportionately affect young adults in low- and middle-income regions. The findings emphasize the need for region-specific prevention strategies integrating smoking cessation, salt reduction, and improved access to early screening and treatment.

February 16, 2026


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