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Alzheimer's Disrupts Circadian Rhythms of Plaque-Clearing Brain Cells

In a study published in Nature Neuroscience, researchers at WashU Medicine found in mice that amyloid accumulations in the brain -- which are characteristic of Alzheimer's disease -- threw off the daily rhythms of hundreds of genes in brain cells known as microglia and astrocytes in ways that were different from what aging alone caused.

October 23, 2025


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