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Boosting Production of Pharmacologically Relevant Diterpenoids Through Engineered Miltiradiene Synthase

A team of researchers has uncovered how subtle structural changes in terpene synthases can dramatically improve the biosynthesis of miltiradiene, a critical intermediate in the production of pharmacologically valuable compounds such as tanshinone IIA, triptolide, and carnosic acid.

October 20, 2025


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