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A New Computational Tool Maps Genome Change, Helping Researchers See DNA in 3D

New research from the Wisconsin Institute for Discovery is tackling a complex packing problem. Thanks to the development of a powerful new computational tool introduced in a study published earlier this year in the journal Genome Research, scientists can better investigate how genomes fit into the tiny confines of a cell nucleus, how they are repackaged across different biological dimensions and how that influences gene expression and disease risk.

August 27, 2025


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